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  • Title: [Renal blood flow after selective injection of different dosages of diatrizoate into the renal artery. An experimental study in the dog (author's transl)].
    Author: Burgener FA, Fischer HW, Weber DA.
    Journal: Rofo; 1975 Oct; 123(4):331-4. PubMed ID: 129391.
    Abstract:
    The characteristic biphasic renal haemodynamic response to diatrizoate injected into the renal artery was shown in the dog with the 133-Xenon washout technique. A brief increase in renal blood flow (RBF) during the first ten seconds is followed by a more prolonged period of diminuished RBF. A dose of 4 ml. diatrizoate 60% resulted in the maximum RBF increase of 43% after ten seconds, but even 1 ml. diatrizoate raised the RBF 24%. The initial vasodilator effect of diatrizoate compares well in its extent with the most potent renal vasodilators.
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