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Title: Transsphenoidal hypophysectomy for four dogs with pituitary ACTH-producing adenoma. Author: Hara Y, Tagawa M, Masuda H, Sako T, Koyama H, Orima H, Nakamura S, Takahashi K, Sanno N, Teramoto A. Journal: J Vet Med Sci; 2003 Jul; 65(7):801-4. PubMed ID: 12939508. Abstract: Four dogs diagnosed as pituitary-dependent hyperadrenocorticism were treated with transsphenoidal hypophysectomy and postoperative hormone supplementation therapy. On histological examination of the resected tissues, the tumors were ACTH-producing adenoma of the anterior lobe. Clinical signs such as alopecia and calcinosis cutis, as well as endocrinological abnormalities, were markedly alleviated after surgery. The clinical courses of these 4 dogs suggest that transsphenoidal hypophysectomy may be a useful treatment for pituitary-dependent hyperadrenocorticism.[Abstract] [Full Text] [Related] [New Search]