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  • Title: [Characteristics of certain components of the systemic inflammatory reaction in patients with diffusive peritonitis].
    Author: Churliaev IuA, Grigor'ev EV, Sherstobitov AV, Sibil' KV, Reĭnik VIa, Martynenkov VIa.
    Journal: Anesteziol Reanimatol; 2003; (2):31-3. PubMed ID: 12939939.
    Abstract:
    The clinical, immunobiochemical and hemostasiological parameters of the systemic inflammatory response (SIR) were studied in 51 patients with diffusive peritonitis. The study showed that lactoferrin, plasminogen/plasmin and alpha 2-macroglobulin can be used, in a set, as informative indices of SIR. A reduced content of lactoferrin, a smaller concentration of proteases inhibitor alpha 2-macroglobulin and a higher relation between plasminogen and plasmin correlate with an unfavorable outcome of the disease beginning from the 1st postoperative day. An activity of Willebrandt's factor is a diagnostic and prognostic marker, which determines a lesion to the endothelium system.
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