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  • Title: [Changes due to age in the regenerating axons of the adult rat].
    Author: Ambrogini P, Cecchini T, Ciaroni S, Del Grande P.
    Journal: Boll Soc Ital Biol Sper; 1992 Oct; 68(10):587-91. PubMed ID: 1295512.
    Abstract:
    Muscle reinnervation after nerve crush was observed in rats at different ages with a combined technique that simultaneously demonstrates nerve endings and endplates. At early times of reinnervation the amount of sprouting was higher in older rats than in younger rats; according to this finding an enhanced number of polyinnervated endplates was found in older rats. A similar enhancement of sprouting and polyinnervation was observed during muscle reinnervation of vitamin E deficient rats, supporting the proposed analogy between vitamin E deficiency and aging.
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