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  • Title: Paranoid psychosis related to mefloquine antimalarial prophylaxis.
    Author: Fuller SJ, Naraqi S, Gilessi G.
    Journal: P N G Med J; 2002; 45(3-4):219-21. PubMed ID: 12968793.
    Abstract:
    Mefloquine is an important antimalarial drug for treatment and prophylaxis of chloroquine-resistant malaria. Its use has been associated with neuropsychiatric side-effects. We report a case of paranoid psychosis associated with mefloquine occurring in a remote part of Papua New Guinea. Adverse reactions and contraindications are discussed. This case underlines the importance of awareness of neuropsychiatric side-effects with mefloquine use and of taking a careful psychiatric history before prescribing mefloquine.
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