These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Simultaneous determination of L- and D-carnitine using a sequential injection analysis/amperometric biosensors system.
    Author: Stefan RI, Bokretsion RG, van Staden JF, Aboul-Enein HY.
    Journal: J Pharm Biomed Anal; 2003 Sep 19; 33(2):323-8. PubMed ID: 12972098.
    Abstract:
    A sequential injection analysis (SIA) system is described for the simultaneous determination of L-and D-carnitine using amperometric biosensors as detectors. The SIA system was used, because of its high precision, accuracy and low sample and buffer consumption. The biosensors were designed using physical and chemical immobilization of L-amino acid oxidase and horseradish peroxidase (HRP) for the assay of L- carnitine, and D-amino acid oxidase and HRP for the assay of D-carnitine. The linear concentration ranges are in the pmol/l to nmol/l magnitude order, with very low limits of detection. The biosensors/SIA system was used reliably for on-line process control of the enantiopurity of carnitine with a frequency of 34 samples per hour.
    [Abstract] [Full Text] [Related] [New Search]