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  • Title: Insulin in the early management of diabetic complications.
    Author: Miles JM.
    Journal: J Assoc Physicians India; 2003 May; 51():501-5. PubMed ID: 12974435.
    Abstract:
    Improved glycemic control reduces microvascular complications in both type 1 and type 2 diabetes. Macrovascular complications predominate in type 2 diabetes, and the effect of tight control here is less clear. Treatment of other aspects of insulin resistance (BP, lipids) significantly reduces cardiovascular morbidity and mortality in type 2 diabetes. Insulin therapy has favorable effects on endothelial function and lipids, especially compared with sulfonylureas. More information is needed on the effects of diabetes pharmacotherapy on cardiovascular outcomes.
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