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  • Title: A corrected transposition of the great arteries with situs inversus visceralis and cleft palate, but without other cardiac defects.
    Author: Kanemoto N, Usui K, Tagawa R, Goto Y.
    Journal: Tokai J Exp Clin Med; 1992 Oct; 17(3-4):115-9. PubMed ID: 1300670.
    Abstract:
    A 17-year-old female admitted for cleft palate surgery was referred for further evaluation of her cardiac condition. The patient had been diagnosed as dextrocardia at birth, without any cardiac murmurs. She has led a normal life. The apical impulse was felt at the fifth intercostal space at the right mid-clavicular line. The ECG and chest x-rays were strongly suggestive of corrected transposition of the great arteries (CTGA) with situs inversus visceralis. Findings of the two-dimensional and Dopplar echocardiograms showed CTGA with a mild morphologic tricuspid regurgitation without any other complicated cardiac anomalies. In the Japanese literature, 36 CTGA patients without associated cardiac defects have been reported. Of these, four patients revealed dextrocardia. To our knowledge, our patient is the first reported adult case without any cardiac defects, only minimal tricuspid regurgitation, situs inversus totalis and cleft palate.
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