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  • Title: Changes in some marker enzyme activities of liver plasma membranes during regeneration after partial hepatectomy in rats.
    Author: Masuda Y, Nishimura T, Nojiri T, Murano T.
    Journal: Biochim Biophys Acta; 1976 Mar 05; 426(2):335-8. PubMed ID: 130167.
    Abstract:
    Liver plasma membranes were isolated from regenerating rat livers between 20 h and 10 days after partial hepatectomy in order to study the effect of partial hepatectomy on some membrane enzyme activities. Mg2+-ATPase (EC 3.6.1.4) activity, but not (Na+ + K+)-ATPase activity, decreased slightly at 2 days, whereas leucyl beta-naphthylamidase (EC3.4.1.1) and 5'-nucleotidase (EC3.1.3.5) activities increased considerably at 1-2 and 3-5 days, respectively. These changes were not parallel to a sharp increase in mitotic activity of liver cells which occurred at 36 h.
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