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Title: [The somatostatin analog SMA (201-995) as adjuvant treatment in patients with external fistulae of the digestive system]. Author: Castañón González JA, Miranda Ruíz R, Arías E, Fuentes Pintado E, Zárate Treviño A. Journal: Gac Med Mex; 1992; 128(3):285-8. PubMed ID: 1302733. Abstract: Six patients with gastrointestinal fistulae treated with a potent inhibitor of gastrointestinal hormones, the somatostatin analogue SMS 201-995 are reported. All patients had severe intraabdominal diseases and underwent a mean of 3.5 surgery procedures during their hospital stay. When the patients were analyzed individually a mean reduction of 42.5% (P < 0.050 of basal fistulae output was observed after treatment. In three patients the fistulae closed after seven and ten days of treatment with the analogue; the other three patients died after a protracted hospital stay which included multiple admissions to the Intensive Care Unit. When the output of all fistulae treated where analyzed together it showed a tendency to decrease, but it didn't reach statistical significance.[Abstract] [Full Text] [Related] [New Search]