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  • Title: Measurement of nerve growth factor-like immunoreactivity in human brain using an anti-mouse-NGF enzyme immunoassay.
    Author: Bertrand P, Roger O, Houlgatte R, Javoy-Agid F, Brandel JP, Doble A, Blanchard JC.
    Journal: Neurochem Int; 1992 Feb; 20(2):215-8. PubMed ID: 1304861.
    Abstract:
    Nerve growth factor (NGF) like immunoreactivity, expressed as mouse 2.5S nerve growth factor equivalents, was evaluated in three structures of the human brain post-mortem using a commercially available enzyme immunoassay. Regional differences in NGF-like immunoreactivity were observed. Highest levels were found in hippocampus (148 pg/g) compared to putamen (76 pg/g) and frontal cortex (34 pg/g). In addition, these results suggest differences in the distribution of brain NGF between human and rodent, where relatively high levels of NGF are found in the cortex.
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