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  • Title: Immunotherapy in two foals with combined immunodeficiency, resulting in graft versus host reaction.
    Author: Ardans AA, Trommershausen-Smith A, Osburn BI, Mayhew IG, Trees C, Park MI, Sawyer M, Stabenfeldt GH.
    Journal: J Am Vet Med Assoc; 1977 Jan 15; 170(2):167-75. PubMed ID: 13055.
    Abstract:
    Immunotherapy was attempted in 2 Arabian foals with combined immunodeficiency. One foal was given a transplant of bone marrow from a selected full sibling, and 1 foal was given a fetal thymus transplant. Both foals died. Genetic evidence was obtained for survival of the transplanted tissues in both cases; however, a graft versus host reaction developed in the foal given the fetal thymus transplant.
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