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  • Title: [The effect of mildronate on erythrocyte membrane permeability in experimental lung pathology].
    Author: Antonenko LI, Frantsuzova SB, Arshinnikova LL.
    Journal: Eksp Klin Farmakol; 1992; 55(6):33-5. PubMed ID: 1305872.
    Abstract:
    With the use of the erythrocyte osmotic and acidic resistance methods, the experiments on intact albino rats by applying a model of chronic non-specific lung diseases and those in vitro have shown that mildronate has a membrane-stabilizing action only when given in high doses (500 mg/kg) and concentrations (10(-3)-10(-4) M). When used in low doses (5, 25, 50, and 200 mg/kg) and concentrations (10(-5)-10(-7) M), in produces no positive effect.
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