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  • Title: Head circumference of children with Down syndrome (0-36 months).
    Author: Palmer CG, Cronk C, Pueschel SM, Wisniewski KE, Laxova R, Crocker AC, Pauli RM.
    Journal: Am J Med Genet; 1992 Jan 01; 42(1):61-7. PubMed ID: 1308367.
    Abstract:
    This study provides statistically appropriate head circumference reference curves for males and females with Down syndrome (DS) from birth to 36 months of age. A total of 239 males and 182 females from five study populations, yielding a combination of cross-sectional and longitudinal data, were used for the analysis. The method of least squares was used to test the fit of the growth model y = a+bx+c[log(x + 1)], where x is age in months. These standardized curves should provide information of value in the medical, physical, and developmental management of children with DS.
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