These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A quantitative study of metachromasy in synovial fluid and mucin.
    Author: HAMERMAN DJ, SCHUBERT M.
    Journal: J Gen Physiol; 1953 Nov 20; 37(2):291-300. PubMed ID: 13109163.
    Abstract:
    SPECTROPHOTOMETRIC MEASUREMENTS ON SYNOVIAL FLUID AND SOLUTIONS OF MUCIN AND HYALURONATE IN THE PRESENCE OF METHYLENE BLUE SHOWED THAT: 1. Dialyzed synovial fluid was not metachromatic. 2. Albumin and gelatin at a concentration of 1 mg. per ml. inhibited the metachromasy of strong chromotropes. 3. Reduction of the protein of synovial fluid by the use of proteolytic enzymes still did not make the synovial fluid chromotropic. 4. Mucin solutions, with a protein content equal to that of protease-treated synovial fluid, were intensely metachromatic. 5. Sulfur-free hyaluronate produced intense metachromasy. The evidence presented indicates that in its native state in synovial fluid hyaluronate is either bound or its anionic groups are not entirely free.
    [Abstract] [Full Text] [Related] [New Search]