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  • Title: [Determination of serum superoxide dismutase, glutathione peroxidase, total antioxidative capacity, malondialdehyde in patients with pneumonia].
    Author: Li GF, He YF, Huang MR, Guo JL, Wu QT, Chen SJ.
    Journal: Di Yi Jun Yi Da Xue Xue Bao; 2003 Sep; 23(9):961-2. PubMed ID: 13129735.
    Abstract:
    OBJECTIVE: To determine the levels of serum superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), total antioxidative capacity (T-AOC) and malondialdehyde (MDA) in patients with pneumonia. METHODS: Sixty-eight patients with pneumonia were divided into group of acute pneumonia, group of chronic bronchitis complicated by lung infection, and group of bronchopneumonia. The levels of serum SOD, GSH-Px, T-AOC and MDA were detected by colorimetry in the 68 patients and 76 normal control subjects. RESULTS: The serum levels of SOD, GSH-Px and MDA were all significantly higher, while T-AOC significantly lower in the 3 patient groups than in the normal subjects. Significant difference in the measurements was also noted between the 3 groups (P < 0.01). CONCLUSION: The determination of serum SOD, GSH-Px, T-AOC and MDA may be helpful for the diagnosis and treatment of pneumonia.
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