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  • Title: [Clinical application of meshed porcine acellular dermis xenograft with split-thickness skin autograft].
    Author: He G, Lin XH, Zhong Q.
    Journal: Di Yi Jun Yi Da Xue Xue Bao; 2003 Sep; 23(9):977-8. PubMed ID: 13129741.
    Abstract:
    OBJECTIVE: To observe the clinical effect of meshed porcine acellular dermis xenograft in conjunction with split- thickness skin autograft in the treatment of full-thickness skin burns and the wound after scar resection. METHOD: Sixteen patients receive the treatment with the skin grafts and the effects of one- and two-stage graftings were compared. RESULTS: In the patient group receiving one-stage grafting, 100% survival rate of the grafts was achieved in 4 cases, 95% in 3 cases, and 80% in 1 case. In two-stage grafting group, 100% survival rate of the grafts was achieved in 5 cases and more than 95% in 3 cases. No cases needed secondary grafting. During the follow-up of the patients for 6 months to 2 years, all the grafts assumed basically normal exterior appearance and texture without obvious scar formation. CONCLUSIONS: The combination of meshed porcine acellular dermis xenograft and split-thickness skin autograft was ideal for repairing full-thickness skin burns, for which one- stage grafting is both simple and practical.
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