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  • Title: Satisfaction with onychomycosis treatment. Pulse versus continuous dosing.
    Author: Warshaw EM, Bowman T, Bodman MA, Kim JJ, Silva S, Mathias SD.
    Journal: J Am Podiatr Med Assoc; 2003; 93(5):373-9. PubMed ID: 13130084.
    Abstract:
    The purpose of this study, which involved two dermatology clinics and two podiatric medical clinics, was to determine whether a difference exists in patient-reported satisfaction and compliance between continuous terbinafine therapy and pulse-dose itraconazole therapy for the treatment of toenail onychomycosis. Patients in this multicenter, open-label, cross-sectional study had previously completed treatment with either oral terbinafine or oral itraconazole for toenail onychomycosis. Patients were interviewed by telephone to assess clinical outcomes, compliance, and satisfaction with treatment; clinical data were collected by medical chart review. Patients reported significantly greater ease and convenience of treatment and higher overall satisfaction with continuous terbinafine therapy compared with pulse-dose itraconazole therapy.
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