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  • Title: [Hyperechogenic fetal bowel: collaborative study of 682 cases].
    Author: Simon-Bouy B, Muller F, Groupe Collaboratif Français.
    Journal: J Gynecol Obstet Biol Reprod (Paris); 2003 Sep; 32(5):459-65. PubMed ID: 13130249.
    Abstract:
    OBJECTIVES: Hyperechogenic fetal bowel is detected in 0.1-1.8% of pregnancies during the second or third trimester. This ultrasound sign is associated with severe pathologies but no large-scale prospective studies have been conducted. MATERIALS AND METHODS: A multicenter study identified 682 cases of hyperechogenic fetal bowel detected by routine ultrasound examination. RESULTS: Pregnancy outcome and postnatal follow-up were obtained in 657 of the 682 cases (96%). In 447 cases (65.5%), a normal birth was observed. Severe multiple malformations were observed in 47 cases (7.1%), a severe chromosomal anomaly in 24 (3.5%), cystic fibrosis in 20 (3%), and viral infection in 19 (2.9%). In utero fetal death occurred in 13 cases (1.9%), a placental and/or maternal pathology in 23 cases (3.5%), IUGR in 28 cases (4.1%) and premature birth in 42 cases (6.2%). CONCLUSION: This study demonstrates the potential severity of this ultrasound sign. Recommended investigations include a detailed scan, fetal karyotyping, cystic fibrosis screening, infectious disease screening. After birth, newborns require pediatric examination because a surgical treatment may be necessary. This should be combined with clear counseling of the parents.
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