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  • Title: Studies on gross footpad lesions of chickens infected with avian reoviruses via the footpad route.
    Author: Takase K, Uchimura T, Yamamoto M.
    Journal: J Vet Med Sci; 1992 Feb; 54(1):23-8. PubMed ID: 1313706.
    Abstract:
    Avian reoviruses grew well in the footpad of chickens inoculated with the viruses via the footpad route, resulting in gross footpad lesions of swelling. The gross footpad lesions induced under some different conditions were investigated for 14 days by two methods. In method A, the lesions were observed grossly and graded as lesion scores 0 to 4. In method B, they were expressed as a swelling index assessed by relative thickness of an inoculated footpad to uninoculated. Both methods are successful, and similar results were obtained. Gross footpad lesions were produced in all chickens aged 9 to 310 days, and the younger were the birds at infection, the earlier and severer were the lesions observed. The lesions began to appear late when the virus titer inoculated was low. It has been elucidated that severity of the lesions depends on virus strains, not on the sexes of chickens.
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