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Title: IgG and IgA antibody responses against porins in Yersinia-triggered reactive arthritis. Author: Mäki-Ikola O, Hill JL, Lahesmaa R, Toivanen A, Granfors K. Journal: Br J Rheumatol; 1992 May; 31(5):315-8. PubMed ID: 1316199. Abstract: Using an enzyme immunoassay, the development and persistence of serum IgG and IgA class antibody responses against porins, a class of the major outer membrane proteins, were compared between patients who developed reactive arthritis and subjects who did not after Yersinia infection. A significant difference was seen between the two patient groups in the beginning of the disease: those with reactive arthritis had higher levels of IgG and IgA class antibodies against the porins. A similar difference in the IgA class antibodies was also seen at follow-up. This supports the hypothesis of persistence of the pathogen within the arthritic host.[Abstract] [Full Text] [Related] [New Search]