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  • Title: [The diagnostic value of enzymes in cerebrospinal fluid (author's transl)].
    Author: Engelhardt P, Avenarius HJ.
    Journal: Med Klin; 1976 Apr 23; 71(17):699-702. PubMed ID: 131904.
    Abstract:
    The clinical value of enzyme activities in cerebrospinal fluid (CSF) should be proved by examination of GOT, GPT, LDH and CPK in blood and CSF of 115 unselected and 4 selected patients. Only the GOT showed a significant correlated increase in diffuse vascular diseases in both, serum and CSF. Discussing the literature the authors affirm, that only mechanical or functional lesion of the blood-brain-barrier will increase the enzyme activities in serum and CSF. The origin of these enzymes however is unknown till now.
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