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  • Title: Disseminated Pneumocystis carinii infection in a hemophiliac patient with acquired immunodeficiency syndrome.
    Author: Wakabayashi T, Oka S, Shimada K, Nakano I, Iwatsubo T, Mori S.
    Journal: Acta Pathol Jpn; 1992 Apr; 42(4):262-6. PubMed ID: 1319101.
    Abstract:
    A case of disseminated Pneumocystis carinii (PC) infection in a 28-year-old Japanese male hemophiliac with acquired immunodeficiency syndrome (AIDS) is reported. The patient had displayed a high fever and diffuse faint interstitial infiltrates on chest X-ray films without dyspnea three months before his death. At that time, no PC was detected after four consecutive induced sputum tests. Serum anti-cytomegalovirus (CMV) IgM was positive by EIA. No treatment for PC and CMV was given at the patient's request. Autopsy findings disclosed disseminated PC infection consisting of granulomas with caseation-like necrosis and frothy exudate in the lungs and disseminated organized calcification in the blood vessels of extrapulmonary organs. PC cysts and/or trophozoites were detected in these lesions.
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