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  • Title: Effect of oat bran on plasma cholesterol and bile acid excretion in nine subjects with ileostomies.
    Author: Zhang JX, Hallmans G, Andersson H, Bosaeus I, Aman P, Tidehag P, Stenling R, Lundin E, Dahlgren S.
    Journal: Am J Clin Nutr; 1992 Jul; 56(1):99-105. PubMed ID: 1319111.
    Abstract:
    A higher excretion of dry matter, fat, nitrogen, energy, and total bile acids in ileal effluents; a lower plasma low-density-lipoprotein (LDL) and total cholesterols (12.1% and 9.0% lower respectively); but no change in plasma high-density-lipoprotein (HDL) cholesterol or apolipoproteins A-I and B were observed in nine subjects with ileostomies when they consumed an oat-bran, bread-based, high-fiber diet (HFD) as compared with a wheat-flour, bread-based, low-fiber diet (LFD) for 3 wk with a crossover design. Of the nine subjects only the subjects with a low daily excretion of bile acids had an elevated excretion of total bile acids during the HFD compared with the LFD. Total cholesterol, LDL cholesterol, and apolipoprotein B in plasma also decreased by 11.3%, 15.3%, and 10.7%, respectively, after consumption of the HFD for 3 wk.
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