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  • Title: [Individual prognosis in endogenous affective and schizoaffective psychoses: biological predictors].
    Author: Evsegneev RA.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1992; 92(1):81-4. PubMed ID: 1319659.
    Abstract:
    A study was made of the distribution of a complex of biological markers: HLA antigens, loci A and B, ABO blood groups, haptoglobin phenotypes, acetylator status, indicators of anthropometry and dermatoglyphics, and marital radius of the parents in 285 patients with affective and schizoaffective psychoses--representatives of the Byelorussian population. The mean time of the clinical follow-up was over 4 years. The magnitudes of relative risk (RR) were computed with regard to the indicated biological signs to estimate their relation to the disease and to some characteristics thereof: polarity of affective disorders, the type of the course, age of manifestation, the presence of homonomous hereditary aggravation, late outcome as well as the efficacy of tricyclic antidepressants and lithium prevention. The data obtained are discussed from the standpoint of their practical use.
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