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  • Title: Synthesis of purine and pyrimidine substituted nitroxides.
    Author: Harcus R, Preston PN, Suffolk JS.
    Journal: Z Naturforsch C Biosci; 1976; 31(1-2):101-2. PubMed ID: 132036.
    Abstract:
    Reaction of 6-hydrazinopurine and 2-hydrazinopyrimidine with 2, 2, 6, 6-tetramethylpiperidone-1-oxyl gives 2, 2, 6, 6-tetramethylpiperidone-1-oxyl-(6-purinyl) hydrazone (3b) and 2, 2, 6, 6-tetramethylpiperidone-1-oxyl-(2-pyrimidinyl) hydrazone (4b) respectively. Compound 3b is inactive even at high dose levels against TLX/5 lymphoma and 3b and 4b are both inactive in tests using the L1210 leukaemia system.
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