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  • Title: The prognostic value of intra-operative observations during thalamotomy for parkinsonian tremor.
    Author: Wester K, Hauglie-Hanssen E.
    Journal: Clin Neurol Neurosurg; 1992; 94(1):25-30. PubMed ID: 1321694.
    Abstract:
    Data from 27 thalamotomies were analyzed with respect to possible correlations between certain intra-operative observations and the long-term effect on parkinsonian tremor. Tremor reduction caused by mechanical impact of the electrodes in the target area was not correlated with the long-term effect on the tremor. The same was true for the threshold intensities during the intra-operative electrical stimulation of the target area, stimulation that facilitates and/or inhibits the tremor. In a minority of the patients, all with good long-term results, a combination of a pronounced tremor inhibition from the electrode insertion and a low threshold intensity was observed. Variations in other lesion parameters were not correlated with the outcome. The results are discussed within the framework of a "tremor" vs. a "tonus" mechanism underlying the thalamotomy effect.
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