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  • Title: [Action of glibenclamide on glucagon and insulin secretions studied on isolated and perfused pancreas of the rat].
    Author: Loubatières AL, Loubatières-Mariani MM, Chapal J, Blayac JP.
    Journal: C R Seances Soc Biol Fil; 1975; 169(6):1568-71. PubMed ID: 132249.
    Abstract:
    Glibenclamide stimulates the insulin secretion by the isolated and perfused rat pancreas, but does not inhibit glucagon secretion when the perfusion liquid contains 1.5 g/I glucose. In the absence of glucose in the perfusion medium, glibenclamide stimulates both insulin and glucagon secretions.
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