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  • Title: Antibodies to hepatitis C virus in kidney transplantation.
    Author: Triolo G, Squiccimarro G, Baldi M, Messina M, Salomone M, Torazza MC, Pratico L, Bonino F, Amoroso A, Segoloni GP.
    Journal: Nephron; 1992; 61(3):276-7. PubMed ID: 1323771.
    Abstract:
    Ninety patients on dialysis, 241 cadaveric kidney donors and 27 cadaveric kidney recipients with a follow-up of 2 years, have been investigated as for anti-HCV positivity by means of 3 tests. As for patients on dialysis and cadaveric donors, the prevalence was 32 and 4%, respectively. As for transplanted patients, it must be noted that 4 negative recipients from positive donors seroconverted, but without any change in hepatic enzymes, while in 2 or 9 anti-HCV-positive recipients, hepatic enzymes increased after transplantation. Seroconversion in patients transplanted from a negative donor was not significantly different. We conclude that, according to their experience, anti-HCV positivity in the donors is not associated with a significant risk of infection in recipients of cadaveric grafts.
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