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Title: Hepatitis C virus in dialysis units: a multicenter study. Author: Da Porto A, Adami A, Susanna F, Calzavara P, Poli P, Castelletto MR, Amici GP, Teodori T, Okolicsanyi L. Journal: Nephron; 1992; 61(3):309-10. PubMed ID: 1323777. Abstract: Three hundred and eighty-seven chronic hemodialysis patients were evaluated, in a multicenter study, to investigate the epidemiology of hepatitis C virus. In anti-HCV seropositive patients, serum ALT values and blood transfusions were retrospectively compared; blood donors were studied for serum transaminases. In seropositive patients without previous blood transfusions, analysis of dialysis schedule was done. Eventually, the intrafamilial transmission of hepatitis C virus was studied in 104 family members. The prevalence of HCV infection in hemodialysis patients was 15.7%. The incidence of acute hepatitis was frequent, while chronic hepatitis incidence was less than expected (17.5%). Intrafamilial diffusion was low (1.9%). Blood-transfusion-related infections seem to be negligible, while cross-contamination in dialysis units seems to be very important.[Abstract] [Full Text] [Related] [New Search]