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  • Title: Autoradiographic evidence of opioid binding sites in rat growth plate chondrocytes.
    Author: Freire-Garabal M, Castaño MT, Belmonte A, Jorge J, Couceiro J, Núñez MJ.
    Journal: Neuroendocrinology; 1992 Mar; 55(3):357-9. PubMed ID: 1323804.
    Abstract:
    After 125I-beta-endorphin was intravenously injected in rats, an autoradiographic study of distal femur growth plates was performed. Results show a specific binding of the radiolabelled peptide to chondrocytes suggesting the possible existence of an opiate modulation of growth plate physiology.
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