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  • Title: Taming effects of p-chlorophenylalanine on the aggressive behavior of septal rats.
    Author: Jones AB, Barchas JD, Eichelman B.
    Journal: Pharmacol Biochem Behav; 1976 Apr; 4(4):397-400. PubMed ID: 132672.
    Abstract:
    Septal irritability and shock-induced aggression were suppressed by the administration of p-chlorophenylalanine (PCPA) to septal rats. The levels of septal irritability and shock-induced fighting were significantly lower in septal, PCPC-treated rats than in nontreated septal rats. Since both parameters of septal aggression were reduced by PCPA, and while PCPA has no effect on shock-induced fighting of unlesioned rats under similar parameters, it appears that both forms of aggression may function through a common neural mechanism.
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