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  • Title: [Changes in T cell subsets and the expression of receptors of transferrin and interleukin-2 in chronic active hepatitis].
    Author: Tang W.
    Journal: Zhonghua Yi Xue Za Zhi; 1992 Feb; 72(2):91-3, 128. PubMed ID: 1327441.
    Abstract:
    The changes of T-cell subsets and expression of transferrin receptor (TFR) and interleukin-2 receptor (IL 2 R) of peripheral blood lymphocyte from patients with chronic active hepatitis (ACH) and chronic serious hepatitis (CSH) were studied. The results showed that T3+ cells were decreased. (P less than 0.01) and T8+ cells were significantly increased (P less than 0.01) in patients with CAH and CSH. TH/TS ratio was markedly decreased in both groups of patients (P less than 0.01). The data also showed that TFR and IL 2 R were in a state of high-expression in resting T-cell, but no obvious changes could be found in the expression of receptor of PHA-stimulated T cells of patients, as compared the controls. The results suggested that some inhibitory factor may be present in the serum of CAH and CSH patients.
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