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  • Title: Mucinous eccrine carcinoma of the eyelid.
    Author: Snow SN, Reizner GT.
    Journal: Cancer; 1992 Oct 15; 70(8):2099-104. PubMed ID: 1327486.
    Abstract:
    BACKGROUND: Mucinous eccrine carcinoma (MEC) is a rare malignant tumor that typically arises in the periorbital area. METHODS: The authors report the 73rd case of primary MEC of the skin. This patient's clinicopathologic findings and the world literature are reviewed. RESULTS: Patient ages range from 8-84 years (median, 63 years). The male-to-female ratio was approximately 2:1. The racial distribution was 67% white, 32% black, and 4% Asian. Primary MEC originates in the head and neck region in approximately 75% of patients. The most common location was the periorbital area (40% or 29 of 73 patients). The local recurrence rate after conventional surgery was: eyelid, 34%; scalp, 36%; and face, 33%. CONCLUSIONS: Primary MEC is often a slow-growing tumor that may recur after traditional surgical excision. Recurrent eyelid MEC tends to be locally destructive with a regional metastatic rate of 3.5% (1 of 29). The regional metastatic rate for all sites was 11%, and the distant metastatic rate was 3%.
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