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  • Title: Isolation of novel lignans, heteroclitins F and G, from the stems of Kadsura heteroclita, and anti-lipid peroxidative actions of heteroclitins A-G and related compounds in the in vitro rat liver homogenate system.
    Author: Yang XW, Miyashiro H, Hattori M, Namba T, Tezuka Y, Kikuchi T, Chen DF, Xu GJ, Hori T, Extine M.
    Journal: Chem Pharm Bull (Tokyo); 1992 Jun; 40(6):1510-6. PubMed ID: 1327562.
    Abstract:
    From the stems of Kadsura heteroclita, two new lignans named heteroclitins F and G were isolated and their structures were determined by various spectroscopic means including an X-ray diffraction method. Dibenzocyclooctadiene type lignans and related compounds isolated from the stems of K. heteroclita, potently inhibited the lipid peroxidation in the rat liver homogenate stimulated by Fe(2+)-ascorbic acid, CCl4-reduced form of nicotinamide adenine dinucleotide phosphate (NADPH) and adenosine 5'-diphosphate-NADPH.
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