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  • Title: Lectin histochemistry of sex cord-stromal tumors and small cell carcinoma of the ovaries.
    Author: Bychkov V, Deligdisch L, Talerman A, Reddy VB.
    Journal: Gynecol Obstet Invest; 1992; 34(2):115-8. PubMed ID: 1327998.
    Abstract:
    Binding sites of peanut agglutinin (PNA), Ulex europaeus (UEA-1), concanavalin A (Con A), and wheat germ agglutinin (WGA) were localized in 10 granulosa cell tumors, 10 Sertoli-Leydig cell tumors, 4 theca cell tumors, and 5 small cell carcinomas. Con A and WGA reacted positively with the majority of the studied neoplasms. PNA and UEA-1 were persistently negative in the sex cord-stromal tumors (SCST) but showed focal positivity in small cell carcinomas. Negative reactions of SCST with PNA and UEA-1 may serve for differentiation between them and common epithelial tumors that are usually PNA and UEA-1 positive.
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