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  • Title: Hepatic rhabdomyomatous tumor: late sequel of a fetal rhabdomyomatous nephroblastoma.
    Author: van der Kwast TH, ten Kate FJ, Vuzevski VD, Madern GC, Terpstra OT.
    Journal: Pediatr Pathol; 1992; 12(3):449-56. PubMed ID: 1329056.
    Abstract:
    A mesenchymal tumor with the macroscopic and microscopic features of a fetal rhabdomyoma arose in the liver of a 14-year-old boy. Thirteen years previously this boy had been treated for a fetal rhabdomyomatous nephroblastoma with nephrectomy and--for subsequent peritoneal disseminations--with surgical excision, radiotherapy, and chemotherapy. The unusual hepatic location of the rhabdomyomatous tumor in this patient supports the view that this mature tumor developed from a metastasis of the original nephroblastoma. As such, this case may represent an example of irreversible change of a malignant process into a benign tumor probably caused by the action of systemic chemotherapy.
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