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  • Title: New antiviral antibiotics, cycloviracins B1 and B2. I. Production, isolation, physico-chemical properties and biological activity.
    Author: Tsunakawa M, Komiyama N, Tenmyo O, Tomita K, Kawano K, Kotake C, Konishi M, Oki T.
    Journal: J Antibiot (Tokyo); 1992 Sep; 45(9):1467-71. PubMed ID: 1331014.
    Abstract:
    Kibdelosporangium albatum No. R761-7 (ATCC 55061) produced new antiviral antibiotics, cycloviracins B1 and B2. They show weak activity against Gram-positive bacteria and potent antiviral activity against herpes simplex virus type 1. Unique acylsaccharide structures were established for cycloviracins B1 and B2 by degradation and spectroscopic analysis.
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