These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: African swine fever virus encodes a gene with extensive homology to type II DNA topoisomerases.
    Author: Baylis SA, Dixon LK, Vydelingum S, Smith GL.
    Journal: J Mol Biol; 1992 Dec 05; 228(3):1003-10. PubMed ID: 1335084.
    Abstract:
    Nucleotide sequencing of a virulent African swine fever virus (ASFV) isolate (Malawi LIL20/1) identified an open reading frame of 1191 amino acid residues encoding a protein of 134.9 kDa. This gene mapped to the SalI i and j restriction endonuclease fragments of the ASFV genome. The predicted polypeptide was found to share 21.1% identity over a 1077 amino acid region with the human type II DNA topoisomerase. The sequence is compared to other type II DNA topoisomerases and the possible roles in ASFV replication are discussed.
    [Abstract] [Full Text] [Related] [New Search]