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  • Title: The interaction of organic cations with the mitochondrial membrane.
    Author: Massari S, Pozzan T.
    Journal: Experientia; 1976; 32(7):868-9. PubMed ID: 133812.
    Abstract:
    Weak and strong organic bases behave in an opposite manner in respect to several mitochondrial functions. The former induce a catalytic exchange with K+ in valinomycon-treated, respiratory-inhibited mitochondria, and act as uncouplers in respiring mitochondria. The latter induce a stoicheometric exchange with K+ and are actively taken up by respiring mitochondria.
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