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  • Title: Synergistic effect of flavones and flavonols against herpes simplex virus type 1 in cell culture. Comparison with the antiviral activity of propolis.
    Author: Amoros M, Simões CM, Girre L, Sauvager F, Cormier M.
    Journal: J Nat Prod; 1992 Dec; 55(12):1732-40. PubMed ID: 1338212.
    Abstract:
    The in vitro activity against herpes simplex virus type 1 of the major flavonoids identified in propolis was investigated. Flavonols were found to be more active than flavones, the order of importance being galangin, kaempferol, and quercetin. The efficacy against HSV-1 of binary flavone-flavonol combinations has been also investigated. The synergy demonstrated by all combinations could explain why propolis is more active than its individual compounds.
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