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  • Title: Fetal and neonatal alloimmune thrombocytopenia: current trends in diagnosis and therapy.
    Author: Kaplan C, Morel-Kopp MC, Clemenceau S, Daffos F, Forestier F, Tchernia G.
    Journal: Transfus Med; 1992 Dec; 2(4):265-71. PubMed ID: 1339580.
    Abstract:
    Neonatal thrombocytopenia affects 20-40% of the infants in intensive care units. The frequency of neonatal alloimmune thrombocytopenia (NAIT) is estimated at 1/1500 to 1/5000 live births. The risk of morbidity is significant with 20% neurological sequelae and the death rate is estimated at 10% of affected infants. During recent years considerable efforts have been made to prevent fetal bleeding and to avoid birth trauma, which have significantly changed the natural history of NAIT.
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