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  • Title: [A gastric multiple neuroendocrine tumor. A case report].
    Author: Giles DM, Bordenave CA.
    Journal: Acta Gastroenterol Latinoam; 1992; 22(3):191-5. PubMed ID: 1341119.
    Abstract:
    A 24-year-old woman underwent an upper digestive hemorrhage. Endoscopy revealed a triple, elevated, submucosal lesion. One of them was ulcerated. A Billroth type I gastrectomy was performed. Post-operative course was uneventful and the patient remained asymptomatic for eighteen month. Histology revealed a monomorphous cellular proliferation, with a rosette-like pattern in some areas and trabecular in others. Histochemical methods confirmed the diagnosis. This one is an infrequent lesion; 0.02% of all gastric tumors. Some research studies have related this kind of tumors with prolonged ingestion of H2 inhibitors and others antacid. These tumors stem from Kultschitzky cells coming from the neuroectoderm. They are scarce in stomach; thus these tumors become infrequent. Effective treatment is endoscopy removal of pedunculated lesions or surgery for the bigger ones.
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