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  • Title: Detection of silent arteriosclerotic lesions by intra-arterial ultrasonography.
    Author: Claessens J, Haseldonckx C.
    Journal: Eur J Med; 1992 Jun; 1(3):139-44. PubMed ID: 1341433.
    Abstract:
    OBJECTIVES: The aim of this study was to detect arteriosclerotic changes in the arterial wall at a preclinical stage. That is at a moment when these arteriosclerotic lesions are still fully asymptomatic and when the usual non-invasive vascular investigation techniques do not show any abnormalities. METHODS: Fifty-six patients with one or more critical stenoses of the coronary arteries, but with a completely normal peripheral vascular examination, were submitted to intravascular ultrasonography of the peripheral arterial system following coronary arteriography. Sonicath Ultrasound catheters were used and images were created with a Diasonics Imaging System. RESULTS: Although these 56 patients, after a profound noninvasive investigation, were classified as having perfectly normal peripheral arteries, we found severe arteriosclerotic wall abnormalities of the abdominal aorta and/or the iliac arterial system in 5% of the subjects. In addition, this exploration technique was used to evaluate the nature and the structure of the registered degenerative arteriosclerotic lesions. CONCLUSIONS: Intra-arterial ultrasonography obviously is a very sensitive investigation method which allows tracing arteriosclerotic changes of the arterial wall in a very early preclinical stage. The external ultrasound exploration techniques still have several important limitations, which, of course, do not hinder the intravascular application. The remaining disadvantage of the intra-arterial ultrasonography is however its invasive character.
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