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  • Title: Efficacy of bi-annual administration of DEC in the control of bancroftian filariasis.
    Author: Balakrishnan N, Ramaiah KD, Pani SP.
    Journal: J Commun Dis; 1992 Jun; 24(2):87-91. PubMed ID: 1344177.
    Abstract:
    The efficacy of bi-annual administration of DEC at the dose of 6 mg/kg body weight was evaluated on the microfilaraemia prevalence, density and vector filarial infection rates. Administration of four doses (4 x 6 mg/kg) of DEC significantly (P < 0.05) reduced the microfilaria rate of the community from 6.02 per cent to 2.31 per cent, microfilaria density from 0.66 to 0.17 and infectivity rate of the vector population from 0.8 per cent to 0.39 per cent.
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