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  • Title: [Haloperidol, reserpine, l-dopa and amantidine in the treatment of Huntington chorea (author's transl)].
    Author: Candelise L.
    Journal: Riv Patol Nerv Ment; 1976; 96(1):54-62. PubMed ID: 134449.
    Abstract:
    Two drugs that should reduce striatal dopamine activity (haloperidol and reserpine) and two other drugs that should increase it (L-Dopa and amantadine) have been successively adminstered to six patients suffering from Huntington's Chorea. The most effective treatment in reducing hyperkinesis was haloperidol, followed by reserpine. Treatment with L-Dopa did not have appreciable effect, on this type of involuntary movements. Against some theoretical expectations administration of amantadine was followed by a slight improvement in the control of involuntary activity.
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