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  • Title: [Primary hypothyroidism in normal thyroid gland morphology].
    Author: Heik SC, Wolf M, Greten H.
    Journal: Fortschr Med; 1992 Feb 28; 110(6):92-3. PubMed ID: 1348235.
    Abstract:
    A 25 year old patient developed hypothyroidism with antibodies against thyroglobulin, thyroid microsomes and thyrotropin receptors. Thyroid 99m-technetium-uptake was 0%. Ultrasound investigation revealed a normal sized, homogenous thyroid gland. Histology showed lymphocyte infiltration but regular follicles. These results suggest the cause of hypothyroidism to be thyrotropin inhibiting immunoglobulins with no parenchyma-destroying properties.
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