These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Neurotoxicity related to lithium and neuroleptic combinations? A retrospective review.
    Author: Kessel JB, Verghese C, Simpson GM.
    Journal: J Psychiatry Neurosci; 1992 Mar; 17(1):28-30. PubMed ID: 1349826.
    Abstract:
    The question of toxic interactions resulting from combinations of lithium and neuroleptic drugs is largely based on anecdotal reports. We replicated the methods of Miller and Menninger (1987) who reported that 27% of manic patients on treatment with lithium and neuroleptics developed toxicity. We found no cases of neurotoxicity as defined in the earlier report. Pharmacologic mechanisms and differences in the clinical findings of the two studies are discussed.
    [Abstract] [Full Text] [Related] [New Search]