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  • Title: Sulfasalazine induced agranulocytosis treated with granulocyte-macrophage colony stimulating factor.
    Author: Kuipers EJ, Vellenga E, de Wolf JT, Hazenberg BP.
    Journal: J Rheumatol; 1992 Apr; 19(4):621-2. PubMed ID: 1350640.
    Abstract:
    We report the use of granulocyte-macrophage colony stimulating factor (GM-CSF) in a case of rheumatoid arthritis with sulfasalazine induced agranulocytosis, leading to a rapid bone marrow recovery within 7 days. This case and 2 others reported in the literature emphasize the need for further research into the possible role of GM-CSF in the treatment of drug induced agranulocytosis.
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