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  • Title: Risk factors in perforated peptic ulcer disease: comparison of a new score system with the Mannheim Peritonitis Index.
    Author: Altaca G, Sayek I, Onat D, Cakmakçi M, Kamiloğlu S.
    Journal: Eur J Surg; 1992 Apr; 158(4):217-21. PubMed ID: 1352135.
    Abstract:
    OBJECTIVE: To construct a score that would accurately predict outcome for patients with perforated peptic ulcers. DESIGN: Retrospective study. SETTING: University Hospital. SUBJECTS: 173 patients who were operated on for perforated peptic duodenal ulcers over a 14 year period. MAIN OUTCOME MEASURES: Results of multivariate discriminant function analysis of derived set of clinical variables known to be associated with high mortality, and comparison with the Mannheim Peritonitis Index. RESULTS: Serious coexisting medical illness, acute renal failure, white cell count of more than 20 x 10(9)/l, and male sex were the most significant factors influencing mortality. The Hacettepe score for perforated peptic ulcer was established using these four variables. The sensitivity was 83%, the specificity 94%, and the overall predictive accuracy 93%. The corresponding figures for the Mannheim Peritonitis Index were 75%, 96%, and 94% respectively. CONCLUSION: The Hacettepe score is useful in predicting whether a patient will survive after perforation of a peptic duodenal ulcer.
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